Rosai-Dorfman Disease.

Rosai-Dorfman Disease (RDD) or Sinus Histiocytosis with massive lymhadenopathy (SHML) is a rare, benign proliferative disorder of histiocytes, sometimes showing familial incidence. It is mainly characterized by painless bilateral cervical lymph node enlargement and is often associated with fever and leucocytosis. It presents in the first or second decades of life, though any age group can be affected. Without the awareness about RDD, the diagnosis of RDD is unexpected especially in South East Asian Countries where certain lymphadenopathies such as tuberculosis, metastatic nasopharayngeal carcinoma and lymphomas are common. RDD is commonly missed and so its revision would seem worthwhile, this case illustrating the disappearance of the lymphadenopathy without treatment.

Partial Androgen Insensitivity Syndrome.

Androgen insensitivity syndrome (AIS) present at several differentiation from genetic defects to end organ resistance thereby producing gender dilema dispelled by sex hormones signature.It is quite traumatic for the patients and family of the affected baby. Extreme sensitivity and awareness on the part of the caring doctor is necessary for early diagnosis of case of AIS &for successful outcome.